GUIDOR easy-graft

 

What raw materials are used to manufacture GUIDOR easy-graft products?
GUIDOR easy-graft products are synthetic materials manufactured from mineral raw materials. They do not contain any substances of animal or human origin.
 
What is the difference between GUIDOR easy-graft CLASSIC and GUIDOR easy-graft CRYSTAL?
GUIDOR easy-graft CLASSIC contains phase-pure ß-tricalcium phosphate (ß-TCP) and is fully resorbable. GUIDOR easy-graft CRYSTAL contains biphasic calcium phosphate (60 % hydroxyapatite, 40 % ß-TCP). It is partially resorbable, the hydroxyapatite remains embedded in the new bone.
 
GUIDOR easy-graft CLASSIC and GUIDOR easy-graft CRYSTAL – How do I decide which material is suitable in a specific case?
The topic of material selection is a matter of clinician and surgical planning preference. See timing/staging of dental implant.
 
Are there two types of granules (HA and ß-TCP) in GUIDOR easy-graft CRYSTAL?
No. Every single granule consists of a compound of 60 % hydroxyapatite and 40 % ß-TCP.
 
How should GUIDOR easy-graft material be condensed?
Experienced GUIDOR easy-graft users use various aids such as flattened stoppers or the plunger of the GUIDOR easy-graft applicator syringe. Over larger areas the material can be evenly condensed by pressing down a piece of gauze (moistened with physiological saline solution) with the finger for 10–30 seconds.
 
Can GUIDOR easy-graft products be used in combination with dental membranes?
Yes, it is at the discretion of the practitioner.
 
When would the use of a membrane be recommended?
GUIDOR easy-graft products are stable and do not require a membrane for containment in 3 or 4 walled defects. Flat (non-concave defects with limited walls) and defects of a critical size may require the additional support of a barrier membrane. Sites where a full thickness periosteal relieving flap is created may also benefit from a barrier membrane for exclusion of soft tissue ingress. The decision to use a membrane is part of therapy planning and is the responsibility of the practitioner.

Does GUIDOR easy-graft adhere to the bone surface?
No. GUIDOR easy-graft products do not adhere to tissue and do not contain adhesives. The granules adhere to one another and form a mouldable mass because of the coating of the granules with PLGA (“sticky granules”).
 
Are GUIDOR easy-graft materials radio opaque?
Yes, GUIDOR easy-graft CLASSIC and GUIDOR easy-graft CRYSTAL are both opaque to x-rays.
 
How long should GUIDOR easy-graft granules be in contact with the BioLinker in the syringe?
The granules must be completely wetted with BioLinker. A complete wetting can be achieved by moving back and forth the plunger and the plug 1 – 3 times. Typically this takes around 20–40 seconds.
 
Should defects be overfilled?
No, the material swells after application. Therefore, overfilling is not recommended.
 
Should the material in the defect be condensed?
GUIDOR easy-graft products should be well condensed in the defect before the material hardens. The round granules withstand compression, therefore, fragments from fractured granules will not form.
 

GUIDOR calc-i-oss

 

What raw materials are used to manufacture GUIDOR calc-i-oss products?
GUIDOR calc-I-oss products are synthetic materials manufactured from mineral raw materials. They do not contain any substances of animal or human origin.

 

What is the difference between GUIDOR calc-i-oss CLASSIC and GUIDOR calc-i-oss CRYSTAL?
calc-i-oss CLASSIC contains phase-pure ß-tricalcium phosphate (ß-TCP) and is resorbed over a period of 5–15 months. calc-i-oss CRYSTAL contains biphasic calcium phosphate (60 % hydroxyapatite, 40 % ß-TCP). It is partially resorbable, the hydroxyapatite remains embedded in the new bone.

 

Are there two types of granules (HA and ß-TCP) in GUIDOR calc-i-oss CRYSTAL?
No. Every single granule consists of a compound of 60 % hydroxyapatite and 40 % ß-TCP.

 

GUIDOR perio-implant diagnostic test

 

How do I send the samples?

Fill in the order form that is provided in the kit and put the samples and the order form into the free-post envelop provided, on which the address is already present. Send the envelope within the day.

 

What kind of analysis is performed in the lab?

The sample is analyzed by real-time PCR, Polymerized Chain Reaction, an in vitro technique of targeted DNA replication. It allows quantitative measurement of the bacteria and assessment of the total bacterial count. Real-time PCR test identifies and quantifies major bone-destroying pathogens and the fungus C.albicans.

 

How long do the paper points need to stay in the periodontal pocket?

Each paper cone should stay approximately 10 seconds into the periodontal pocket and then put into the test tube provided.

 

Why are reports colour-coded?

Socransky has classified sub-gingival flora into different associated complexes, each of them characterized by a different color reflecting the degree of their pathogenic potential and requiring specific antibiotic treatment.

 

Why would a test be needed?

To check the periodontal status before implant placement, especially if the patient had previously been diagnosed (and consequently treated) with periodontal disease. To check the periodontal status after periodontal treatment and also after implant placement, in the maintenance regimen to ensure early diagnosis of a potential inflammation around teeth or implants. To help diagnose some specific periodontal disease that might persist despite treatment.

 

Why is Candida albicans also analyzed?

In addition to the pathogenic bacteria, the fungus C. albicans is capable of colonizing the periodontal pockets in patients with chronic periodontitis and has been identified in the subgingiva of healthy individuals and patients with aggressive periodontitis (Urzúa B, et al. 2008). It is recovered from periodontal pockets in 7.1% to 19.6% of patients with chronic periodontitis. (Sardi JC et al. 2010).

 

Why is it the same test for periodontal pockets and perio-implantitis?

Inflammatory diseases such as periodontitis and peri-implantitis are caused by a similar group of periodontal pathogens, with different degrees of pathogenic potential. These microorganisms colonize the periodontal pockets, causing inflammation of the gingival tissues and progressive bone loss. Not all periodonto-pathogens are attributed the same significance though: periodontal disease and implant complications are associated with certain identified microbiota.


GUIDOR Periocline Dental Ointment

 

Can Periocline stay out of the fridge?

To keep its properties intact, Periocline needs to be stored between 2-8°C, i.e. in the fridge.

 

Can the patient eat after the application of Periocline?

After application of Periocline, it is recommended that the patient avoids eating, drinking, brushing, rinsing and flossing for at least 2 hours.

 

If there is product left in the syringe, can I re-use the same syringe for the next application on the same patient?

No, each syringe is for single-use. We recommend that you properly discard the syringe once you have finished your application and that you use a new syringe for the following application.

 

On which bacteria is minocycline active?

Minocycline has proved to be effective on Aggregatibacter actinomycetencomitans, Pophyromonas gingivalis, Prevotella intermedia, Tannerella forsythia, Eikenella corrodens and Treponema denticola, which are recognized periodontal pathogens.

 

What is the Eudragit process?

The active ingredient Minocycline is micro-encapsulated in a polymer through our Eudragit process. In contact with the gingival fluids, the polymer slowly degrades and gradually releases the minocycline into the pocket.

 

Note: please refer to local IFU for more specific indications.